Cardio-Pulmonary Combined Genetic Testing
Dual-panel insights into cardiovascular and pulmonary risks
Introduction
Comprehensive Heart and Lung Genetics
This panel evaluates genes linked to inherited cardiac and pulmonary conditions, including cardiomyopathies, arrhythmias, aortopathies, Cystic Fibrosis, Alpha-1 Antitrypsin Deficiency, and primary ciliary dyskinesia. It supports early identification of at-risk individuals, guiding preventive care, lifestyle modifications, and personalized treatment strategies. The results also assist in family screening and long-term management of complex, multisystemic disorders.
Why the Test Is Significant
Prevents Cardiac Emergencies
Identifies genetic risks for sudden cardiac death
Clarifies Cardiac Diagnoses
Detects conditions like HCM and long QT syndrome
Confirms Lung Disease Origins
Diagnoses inherited pulmonary disorders
Enables Family Risk Screening
Helps detect at-risk relatives through cascade genetic testing
Unknown and Interesting Facts
Some genetic heart rhythm disorders, known as channelopathies, can lead to sudden cardiac death in individuals with no structural heart abnormalities and no prior symptoms. Additionally, Alpha-1 Antitrypsin Deficiency—a hereditary condition affecting lung and liver function—is relatively common yet frequently underdiagnosed. Combined genetic testing provides a broader view, revealing dual-system risks that might otherwise be overlooked in standard evaluations, enabling early detection and targeted preventive care.
Medical Necessity and Signs/Symptoms
- Family history of sudden death under age 50
- Personal or family history of cardiomyopathy or arrhythmia
- Known or suspected inherited lung diseases
- Unexplained fainting, seizures, or heart palpitations
- Shortness of breath without clear cause
- Congenital heart abnormalities or characteristic EKG patterns
- Symptoms suggesting cystic fibrosis or Alpha-1 Antitrypsin Deficiency
- Need for combined cardiac and pulmonary risk assessment
Post-Test Support
Elite Clinical Laboratory provides comprehensive interpretation support, helping clinicians understand the cardiac and pulmonary implications of genetic findings. We facilitate access to genetic counselors and foster collaboration with both cardiologists and pulmonologists to develop personalized management plans. Our goal is to bridge complex diagnostic data with clinical care, guiding surveillance, prevention, and therapeutic decisions for patients with combined hereditary risk factors.