Hereditary Neurological Disorders Risk Panel
Genetic insights guiding neurological care decisions
Introduction
Genetic Clarity for Neurological Disorders
This comprehensive panel examines genes associated with a wide range of inherited neurological conditions, such as epilepsy, movement disorders (including dystonia and Parkinsonism), peripheral neuropathies, muscular dystrophies, neurodegenerative diseases, and developmental brain disorders. It supports precise diagnosis, helps clarify complex clinical presentations, and guides prognosis, treatment decisions, and family planning for individuals with suspected genetic neurological conditions.
Why the Test Is Significant
Confirms Diagnosis
Ends prolonged diagnostic odysseys with precise genetic answers.
Informs Prognosis
Supports understanding of potential clinical progression.
Guides Treatment
Guides therapy selection and personalized management strategies.
Assesses Family Risk
Identifies at-risk relatives for early intervention and planning.
Unknown and Interesting Facts
Hereditary neurological conditions often present diagnostic challenges due to variable expressivity—where individuals with the same mutation may experience vastly different symptoms—and incomplete penetrance, meaning not everyone with a pathogenic variant will show signs of disease. These factors can obscure diagnosis without genetic testing. Advancements in genomics are reshaping how clinicians classify and manage conditions like epilepsy, ataxia, and neuropathies, helping to uncover previously unrecognized hereditary patterns.
Medical Necessity and Signs/Symptoms
- Unexplained seizures or epilepsy
- Movement disorders (tremor, dystonia, ataxia)
- Muscle weakness or progressive atrophy
- Developmental regression or delay
- Peripheral neuropathy (numbness, pain, tingling)
- Abnormal gait or coordination issues
- Positive family history of neurological disorders
- Unusual findings on brain imaging or EEG
Post-Test Support
Elite Clinical Laboratory delivers comprehensive result interpretation, helping providers navigate the complex genetics of neurological disorders. We offer consultation pathways to genetic counselors trained in neurology, enabling in-depth discussions about recurrence risks, disease prognosis, and treatment eligibility. Our support extends to helping families access specialized care, such as neurology referrals or enrollment in clinical trials, ensuring that test findings translate into proactive patient care strategies.